Ask any biological question. AI decomposes it into NCBI searches, retrieves results, and synthesizes an answer.
Search across NCBI Nucleotide, NCBI Protein, NCBI Gene, UniProt, and PDB simultaneously
Paste or fetch a DNA sequence. Runs composition, codon usage, ENC, Ts/Tv, dinucleotide, GC skew, CpG analysis.
RNA secondary structure prediction (ViennaRNA RNAfold).
Protein properties (MW, GRAVY, charge), amino acid composition, hydrophobicity plot.
MAFFT alignment, genetic distance matrices (p-distance, JC, K2P, TN93).
Tree building, Bayesian dating, saturation testing, recombination detection.
Simulate molecular evolution with customizable parameters. Fetch real sequences from NCBI or use random DNA.
Optimize codon usage for maximum protein expression in your target host organism.
Choose a research domain โ narrow your focus step by step โ discover genes, pathways, and therapeutic targets.
Click any gene to search for its 3D protein structure in PDB
Ask about protein structures, functions, or drug targets. AI searches UniProt + PDB + AlphaFold simultaneously.
Search protein structures from PDB, view 3D models, and analyze protein sequences.
Compare 2+ protein sequences โ identity, similarity, key mutations, conservation profile.
GPU-accelerated multi-sequence analysis for drug discovery and medical diagnostics. Add sequences by NCBI accession or paste directly.
Regions scored by conservation, functional importance, and resistance risk
Bridge traditional medicine with modern pharmacology. Compare natural compounds against Western drugs through shared molecular targets and structural similarity.
Search any compound to view its structure and compare
Search across ChEMBL (2M+ bioactive compounds), PubChem, and UniProt targets simultaneously
Analyze nootropic products by their molecular mechanisms. See which neural pathways each product targets and compare evidence quality.
Comparative study of plant and human stem cell regulatory networks โ Gurbachan Singh
Species: Arabidopsis thaliana, Mus musculus, Homo sapiens, Hydra vulgaris, C. elegans | Focus: Mesenchymal Stem Cells
MAFFT alignment โ IQ-TREE phylogenetics โ AlphaFold3 structure prediction. Server-side computation on Tesla P40.
Paste sequences in FASTA format or add NCBI accessions. Supports DNA and protein.
Automatic model selection (ModelFinder) + ultrafast bootstrap. Run MAFFT first or paste aligned FASTA.
Search by gene name or UniProt ID to view AlphaFold predicted 3D structures with confidence scores.
Predict minimum free energy (MFE) structure using ViennaRNA. Paste RNA or DNA (auto-converts TโU).
Find hidden regulatory motifs in promoter sequences. Paste 3+ sequences in FASTA format.
Tests whether sequences retain enough phylogenetic signal. Run BEFORE building trees. If saturated, tree topology may be unreliable.
Run MAFFT first, then click below to test the alignment.
Sliding window similarity analysis to detect recombination breakpoints. Essential for HIV, SARS-CoV-2, and other recombining viruses.
MCMC-based divergence time estimation. Runs on Tesla P40 at .200. Run MAFFT first to provide alignment.
Automatically scans Europe PMC daily for new publications across 12 tracked research topics. Papers from the last 48 hours are flagged.
Multi-database analysis with epigenetic convergence. Queries NCBI + KEGG + STRING + WikiPathways + Open Targets + DisGeNET + Ensembl + STITCH simultaneously, then AI synthesizes cross-domain connections.
๐ก Ask in natural language โ the AI decomposes your query into genes, compounds, diseases, and pathways, then fans out across 8+ databases.
Epigenetic regulators found in the interaction network โ the control layer connecting all domains.
Diseases linked to 2+ of your query genes โ where seemingly unrelated domains meet.
Natural dietary compounds that target genes in your query network. Matched from 18 curated nutrigenomic compounds.
Latest publications matching your query genes. Sorted by publication date (newest first).
Enter gene names to visualize their pathway interactions, protein networks, and signaling diagrams.
Confidence-weighted interactions between your genes. Thicker lines = stronger evidence.
Metabolic and signaling pathway maps from KEGG. Your genes are highlighted in the diagrams.
Curated human pathway diagrams from Reactome.
Select your area of concern โ see the gene pathways involved โ get product recommendations backed by genomic research.
These genes control hair growth in your selected zone. Click any gene to view in NCBI.
Real-world products ranked by pathway match strength. Rating reflects genomic evidence quality.
Compare two protein structures (PDB or AlphaFold). Computes RMSD, per-residue deviation, domain conservation, and AI interpretation.
Dock small molecules against protein targets using AutoDock Vina on Tesla P40 GPU. Predicts binding affinity and drug-likeness.
Swiss Institute of Bioinformatics tools recommended by Xia (2017) for drug discovery. Enter a SMILES to generate pre-filled launch links.
Explore medicinal fungi and their psychoactive compounds โ molecular targets, neural pathways, therapeutic potential, and genomic basis of neuroactive metabolite production.
Describe your symptoms or condition in plain English. AI matches you with medicinal fungi, explains mechanisms, and suggests analysis tools.